2025
2025
2024
MightyMoieties
Albumax Edition focuses on cephalosporins, one of the most widely used classes of antibiotics. We designed albumin binding proteins to link the antibiotic to albumin, extending its half-life.
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2023
Byephenyl
We computationally redesigned a non-oxygen-sensitive dehalogenase to potentially have a binding efficiency to highly chlorinated PCBs for environmental remediation.
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2022
WaMel
A paper-based point of care diagnostic test for early detection of melanoma, combined with peptide-based anti-cancer therapeutics.
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2021
RhizoMet
Modified human metallothionein IA protein to have all 7 binding sites specific to arsenic, enabling environmental arsenic remediation.
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2019
Immunosense
Combining chemically induced dimerization with luciferase assays to create biosensors that luminesce when target molecules are detected.
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2018
Stronger Together
Novel strategy to select CID binders from a combinatorial nanobody library, creating new CID systems that sense cholecalciferol and artemisinin.
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2017
Viva La Violacein: Tracker
Real-time, automated analysis of metabolic products in an adjustable turbidostat to reduce time and effort in culture maintenance.
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2016
Viva la Violacein
Autonomous control system for yeast cultures using colored gene expression signals processed by computer to release inducers as needed.
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2015
Lab on a Strip
Cheap diagnostic tool with genetically-modified baker's yeast grown on paper, producing easy-to-read color output for target molecules.
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2014
High Throughput Selection
Generalizable, high throughput method to select for increased expression and stability of engineered proteins for large-scale production.
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2013
Red Light, Green Light
Development and characterization of tools for multichromatic gene expression in synthetic biology applications.
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2012
AppTOGenetics
Methods to optimize biological systems through directed evolution, light-regulated gene expression, and computer-aided protein design.
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2011
Make It or Break It
Diesel production and gluten destruction using synthetic biology to meet world needs for fuel and medicine.
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2010
Antibiotics for the 21st Century
Re-engineered enzyme to remove Bacillus anthracis protective coating, rendering the anthrax pathogen defenseless against immune system.
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2009
Ideal Protein Purification
All-in-one protein expression and purification platform built on BioBrick standards to reduce costs and simplify procedures.
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2008
Vector-Jector
Controlling genetic material transfer across phylogenetic domains, directing E. coli to transfer DNA to yeast S. cerevisiae.
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