2024
MightyMoieties
Albumax Edition focuses on cephalosporins, one of the most widely used classes of antibiotics. We designed albumin binding proteins to link the antibiotic to albumin, extending its half-life.
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2024
2023
Byephenyl
We computationally redesigned a non-oxygen-sensitive dehalogenase to potentially have a binding efficiency to highly chlorinated PCBs for environmental remediation.
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2022
WaMel
A paper-based point of care diagnostic test for early detection of melanoma, combined with peptide-based anti-cancer therapeutics.
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2021
RhizoMet
Modified human metallothionein IA protein to have all 7 binding sites specific to arsenic, enabling environmental arsenic remediation.
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2019
Immunosense
Combining chemically induced dimerization with luciferase assays to create biosensors that luminesce when target molecules are detected.
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2018
Stronger Together
Novel strategy to select CID binders from a combinatorial nanobody library, creating new CID systems that sense cholecalciferol and artemisinin.
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2017
Viva La Violacein: Tracker
Real-time, automated analysis of metabolic products in an adjustable turbidostat to reduce time and effort in culture maintenance.
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2016
Viva la Violacein
Autonomous control system for yeast cultures using colored gene expression signals processed by computer to release inducers as needed.
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2015
Lab on a Strip
Cheap diagnostic tool with genetically-modified baker's yeast grown on paper, producing easy-to-read color output for target molecules.
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2014
High Throughput Selection
Generalizable, high throughput method to select for increased expression and stability of engineered proteins for large-scale production.
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2013
Red Light, Green Light
Development and characterization of tools for multichromatic gene expression in synthetic biology applications.
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2012
AppTOGenetics
Methods to optimize biological systems through directed evolution, light-regulated gene expression, and computer-aided protein design.
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2011
Make It or Break It
Diesel production and gluten destruction using synthetic biology to meet world needs for fuel and medicine.
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2010
Antibiotics for the 21st Century
Re-engineered enzyme to remove Bacillus anthracis protective coating, rendering the anthrax pathogen defenseless against immune system.
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2009
Ideal Protein Purification
All-in-one protein expression and purification platform built on BioBrick standards to reduce costs and simplify procedures.
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2008
Vector-Jector
Controlling genetic material transfer across phylogenetic domains, directing E. coli to transfer DNA to yeast S. cerevisiae.
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